Use of a soluble recombinant human cd40l protein for...

Details Use of a soluble recombinant human cd40l protein for... Use of a soluble recombinant human cd40l protein for...

A - Human Necessities

61

K

A61K 38/17 (2006.01) A01K 67/027 (2006.01) G01N 33/48 (2006.01)

Patent

CA 2311679

The invention relates to a method for inhibiting in vivo immune response and to the use of a soluble recombinant human CD40L or a sequence within said soluble recombinant human CD40L containing the active binding site with CD40 for inhibiting an immune response. The invention also relates to a mouse model of human alloimmunization for testing in vivo effects of an immunotherapy or inhibition of a human antibody response.

L'invention concerne un procédé servant à inhiber une réponse immune in vivo et l'utilisation d'une CD40L soluble humaine de recombinaison ou d'une séquence de ladite CD40L soluble humaine de recombinaison contenant le site de fixation actif avec CD40 afin d'inhiber une réponse immune. Elle concerne également un modèle de souris d'allo-immunisation humaine servant à tester les effets in vivo d'une immunothérapie ou d'une inhibition de la réponse humaine aux anticorps.

Affiliated with

Also associated with

Rating

Use of a soluble recombinant human cd40l protein for... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Use of a soluble recombinant human cd40l protein for..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Use of a soluble recombinant human cd40l protein for... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1541202