Use of a statin derivative in the treatment of eye complaints

Details Use of a statin derivative in the treatment of eye complaints Use of a statin derivative in the treatment of eye complaints

A - Human Necessities

61

K

A61K 38/07 (2006.01) A61K 38/00 (2006.01) A61K 38/55 (2006.01)

Patent

CA 2018209

IN THE UNITED STATES PATENT AND TRADEMARK OFFICE PATENT APPLICATION entltled: Use of a statin derivative in the treatment of eye complaints in the name of: Dino NISATO Gérard LE FUR Assignee: SANOFI ABSTRACT OF THE DISCLOSURE The invention relates to the use of N-(3-pyridyl- propionyl)phenylalanylhistidyl(cyclohexyl)staty1-N-(1,3- dihydroxy-2-methylpropyl)isoleucinamide, which has the formula Image ( I) in which: Phe is the (L)-phenylalanine residue, His is the (L)-histidine residue, Ile is the (L)-isoleucine residue and (cyclohexyl)Sta is the cyclohexylstatin residue, i.e the (3S, 4S)-4-amino-5-cyclohexyl-3- hydroxypentanoic acid residue, for the preparation of drugs useful in the treatment of eye complaints. Application: treatment of eye complaints.

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