C - Chemistry – Metallurgy – 12 – N
Patent
C - Chemistry, Metallurgy
12
N
C12N 15/00 (2006.01) A01K 67/027 (2006.01) C12N 5/10 (2006.01) C12N 9/16 (2006.01) C12N 15/85 (2006.01) C12N 15/86 (2006.01) C12N 15/89 (2006.01)
Patent
CA 2419505
The present invention provides an isolated animal cell comprising an exogenous nucleic acid encoding a mutated phytase, wherein the cell produces phytase and secretes the phytase from the cell. The present invention also provides an animal having a phenotype not naturally occurring, characterized by secretion of phytase into the lumen of the gastrointestinal tract of the animal, the phenotype being conferred by a transgene contained in the cells of the animal, the transgene comprising a nucleic acid sequence encoding phytase and methods of making said animal.
L'invention concerne une cellule animale isolée comportant un acide nucléique exogène codant une phytase mutante, ladite cellule produisant et sécrétant la phytase. La présente invention concerne également un animal présentant un phénotype n'existant pas à l'état naturel, caractérisé par sécrétion de phytase dans la lumière du tractus gastro-intestinal de l'animal, le phénotype produit par un transgène contenu dans les cellules de l'animal, le transgène comportant une séquence d'acides nucléiques codant la phytase, ainsi que des procédés destinés à créer ledit animal.
Petitte James
Reynolds Paul
Shears Stephen
North Carolina State University
Sim & Mcburney
The Government Of The United States Of America
University Of Rochester
LandOfFree
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