Use of a vegf antagonist in combination with radiation therapy

Details Use of a vegf antagonist in combination with radiation therapy Use of a vegf antagonist in combination with radiation therapy

A - Human Necessities

61

K

A61K 38/18 (2006.01) A61K 45/00 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2534197

Methods of treating cancer and/or reducing or inhibiting tumor growth in a subject in need thereof, comprising administering pharmaceutical composition comprising a vascular endothelial cell growth factor (VEGF) inhibitor or trap, such as the VEGF trap of SEQ ID NO: 1 or SEQ ID NO:3, in combination with radiation therapy, including ionization radiation and/or a therapeutic radiopharmaceutical.

La présente invention se rapporte à des méthodes permettant de traiter un cancer et/ou de réduire ou d'inhiber la croissance tumorale chez un sujet concerné. Lesdites méthodes consistent à administrer une composition pharmaceutique contenant un inhibiteur ou un piège des facteurs de croissance des cellules endothéliales vasculaires (VEGF), tel que le piège des VEGF de SEQ ID NO:1 ou SEQ ID NO:3, et d'effectuer en parallèle une radiothérapie, laquelle consiste en un rayonnement par ionisation et/ou un produit radiopharmaceutique.

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