Use of a virus expressing a binding moiety to measure...

Details Use of a virus expressing a binding moiety to measure... Use of a virus expressing a binding moiety to measure...

C - Chemistry, Metallurgy

12

Q

C12Q 1/70 (2006.01) C12N 7/01 (2006.01) C12Q 1/68 (2006.01) G01N 33/543 (2006.01) G01N 33/569 (2006.01)

Patent

CA 2518036

The use of a virus, which expresses and displays a binding moiety, as a means of detecting the presence or measuring the concentration of an analyte in a sample. The virus, which is typically a bacteriophage expressing a binding moiety, is used as a binding reagent in an immunoassay, and may be readily and accurately detected by detecting nucleic acid sequences of the virus.

La présente invention porte sur l'utilisation d'un virus exprimant et présentant un fragment de liaison pour détecter la présence ou mesurer la concentration d'un analyte dans un échantillon. Ce virus, qui est d'ordinaire un bactériophage exprimant un fragment de liaison, sert de réactif de liaison dans un immuno-essai et peut être détecté immédiatement et précisément par la détection de séquences d'acides nucléiques du virus.

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