G - Physics – 01 – N
Patent
G - Physics
01
N
G01N 33/574 (2006.01) C12Q 1/68 (2006.01) G01N 33/68 (2006.01)
Patent
CA 2709678
The present invention is based on the discovery of the tumor suppressor role of activating transcription factor 2 (ATF2) in non-melanoma skin cancer development. Accordingly, the invention provides methods of diagnosing a subject as having or at risk of having skin cancer. Also provided are methods of treating skin cancer in a subject, characterizing skin cancer in a subject, and identifying agents useful for treating skin cancer in a subject.
La présente invention repose sur la découverte du rôle de suppresseur tumoral de l'activation du facteur de transcription 2 (ATF2) dans le développement du cancer de la peau non mélanome. Par conséquent, l'invention concerne des procédés permettant le diagnostic d'un sujet comme présentant ou à risque de développer un cancer de la peau. L'invention concerne également des procédés de traitement du cancer de la peau chez un sujet, la caractérisation du cancer de la peau chez un sujet, et l'identification d'agents utiles pour le traitement du cancer de la peau chez un sujet.
Bhoumik Anindita
Ronai Ze'ev
Burnham Institute For Medical Research
Mbm Intellectual Property Law Llp
LandOfFree
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