Use of adrenergic alpha2b antagonists for the treatment of...

Details Use of adrenergic alpha2b antagonists for the treatment of... Use of adrenergic alpha2b antagonists for the treatment of...

A - Human Necessities

61

K

A61K 31/00 (2006.01)

Patent

CA 2539757

The present invention relates to selective adrenergica2B antagonists alone, selective adrenergic.alpha.2B antagonists in combination with norepinephrine reuptake inhibitors (NRI) (as a single compound or as a combination of two or more compounds), or selective adrenergic.alpha.2B antagonists in combination with dual norepinephrine reuptake inhibitors/serotonin reuptake inhibitors (NRI/SRI) (as a single compound or as a combination of two or more compounds) and methods of their use in the treatment of vasomotor symptoms.

L'invention concerne des antagonistes adrénergiquesa<SUB>2B</SUB> sélectifs, isolément, et ces mêmes antagonistes combinés avec des inhibiteurs de réabsorption de norépinéphrine (NRI) (en composé unique ou en combinaison avec deux ou plus de deux composés), ou bien ces mêmes antagonistes combinés avec des inhibiteurs doubles de réabsorption de norépinéphrine /sérotonine (NRI/SRI) (en composé unique ou en combinaison avec deux ou plus de deux composés), ainsi que des procédés d'utilisation correspondants pour le traitement des symptômes vasomoteurs.

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