Use of agonists or antagonists of mip-3a in therapy

C - Chemistry – Metallurgy – 07 – K

Patent

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C07K 14/52 (2006.01) A61K 38/19 (2006.01) A61P 17/00 (2006.01) A61P 35/00 (2006.01) A61P 37/06 (2006.01) C07K 14/715 (2006.01) C07K 16/24 (2006.01) C07K 16/28 (2006.01) C12N 5/06 (2006.01)

Patent

CA 2362091

Agonists or antagonists of MIP-3.alpha., and various methods of use in dermatological and related applications are provided. In particular, the method makes use of fact that the MIP-3.alpha. chemokine is specifically capable of inducing migration of a skin cell subset.

L'invention se rapporte à des agonistes et à des antagonistes de la chimiokine MIP-3.alpha. et à diverses méthodes d'utilisation dans des applications dermatologiques et associées. Ces méthodes sont fondées notamment sur le fait que la chimiokine MIP-3.alpha. possède une capacité spécifique d'induction de la migration d'un sous-ensemble cellulaire de la peau.

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