Use of alkylating compounds for inhibiting proliferation of...

A - Human Necessities – 61 – K

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A61K 31/473 (2006.01) A61K 31/00 (2006.01) A61K 47/48 (2006.01)

Patent

CA 2332314

The present invention provides methods and compositions for inhibiting the proliferation of smooth muscle cells at a site of vascular injury. The methods include intravascular administration of a reactive compound to the site of injury, without the requirement for activation or sustained release of the compound.

L'invention concerne des procédés et des compositions qui permettent d'inhiber la prolifération des cellules musculaires lisses sur un site de blessure vasculaire. Les procédés décrits consistent notamment en une administration intravasculaire de composé réactif sur le site de la blessure, sans qu'il soit nécessaire d'activer ou de prolonger la libération du composé.

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