Use of allopurinol for the treatment of hand foot skin reaction

Details Use of allopurinol for the treatment of hand foot skin reaction Use of allopurinol for the treatment of hand foot skin reaction

A - Human Necessities

61

K

A61K 31/519 (2006.01) A61K 9/00 (2006.01) A61K 31/52 (2006.01) A61P 17/02 (2006.01)

Patent

CA 2759085

Use of allopurinol or a pharmaceutically acceptable salt thereof for the treatment or prevention of Hand Foot Skin Reaction (HFSR) induced by Multitargeted Kinase Inhibitor (MKI) therapy. The allopurinol or its salt is administered topically to the affected areas, palms and soles, preferably in the form of a cream.

Cette invention concerne l'utilisation de l'allopurinol ou de son sel pharmaceutiquement acceptable dans le traitement ou la prévention du syndrome d'enflure des mains et des pieds induits par un traitement à base d'inhibiteurs multi-cibles des kinases. L'allopurinol ou son sel est administré topiquement sur les zones affectées, la paume des mains et la plante des pieds, de préférence sous forme de crème.

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