Use of .alpha.1ar subtype-selective drugs in patients with...

A - Human Necessities – 61 – K

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A61K 31/50 (2006.01) A61K 31/19 (2006.01) A61K 31/44 (2006.01) G01N 33/94 (2006.01)

Patent

CA 2393488

The present invention relates to the use of .alpha.1aAR-selective and/or .alpha.1a/.alpha.1d-selective antagonists in a method of preventing restenosis after myocardial infarction and re-perfusion. The invention further relates to a method of identifying agents suitable for us in such a method.

L'invention concerne l'utilisation d'antagonistes présentant une sélectivité pour .alpha.¿1a?AR et/ou .alpha.¿1a?/.alpha.¿1d? dans un procédé servant à éviter la restènose après un infarctus du myocarde et une reperfusion. Elle concerne, de plus, un procédé servant à identifier des agents pouvant être mis en application dans ce premier procédé.

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