A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/355 (2006.01) A61K 31/352 (2006.01) A61P 25/14 (2006.01) A61P 25/16 (2006.01) A61P 25/28 (2006.01)
Patent
CA 2580584
The invention relates the method of treatment or amelioration of mitochondrial disorders such as Alzheimer's disease, Parkinson's disease, Friedreich's ataxia (FRDA), cerebellar ataxias, Leber's hereditary optic neuropathy (LHON), mitochondrial myopathy, encephalopathy, lactacidosis, stroke (MELAS), Myoclonic Epilepsy with Ragged Red Fibers (MERFF), amyotrophic lateral sclerosis (ALS), motor neuron diseases, Huntington's disease, macular degeneration, and epilepsy, with chroman derivatives of Formula I or Formula II as described herein.
La présente invention a trait à un procédé de traitement ou d'amélioration de troubles mitochondriaux tels que la maladie d'Alzheimer, la maladie de Parkinson, l'ataxie de Friedreich, les ataxies cérébelleuse, la neuropathie optique héréditaire de Leber, la myopathie mithochondriale, l'encéphalopathie, la lactacidose, l'accident vasculaire cérébral (MELAS), l'épilepsie myoclonique à fibres rouges en lambeaux, la sclérose latérale amyotrophique, les maladies des motoneurones, la maladie de Huntington, la dégénération maculaire, et l'épilepsie, avec des dérivés chromanes de formule (I) ou de formule (II) telles que définies dans la description.
Boddupalli Sekhar
Miller Guy
Walkinshaw Gail
Wang Bing
Ampere Life Sciences Inc.
Borden Ladner Gervais Llp
Galileo Pharmaceuticals Inc.
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