Use of .alpha.-w-dicarboxylic acids as fibrinogen sinkers

A - Human Necessities – 61 – K

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A61K 31/20 (2006.01) A61K 31/405 (2006.01) A61K 31/445 (2006.01) A61K 31/495 (2006.01)

Patent

CA 2138128

-15- Summary Compounds of .alpha.,.omega.-dicarboxylic acids of the formula I Image (I) in which X and Y, which can be the same or different, signify hydrogen, halogen, C1-C6-alkyl, C1-C6- alkoxy, hydroxyl, cyano, carboxyl, C1-C6-alkoxy- carbonyl or carbamoyl, R1 and R2, which can be the same or different, hydrogen or C1-C6-alkyl and Q a linear saturated or unsaturated alkylene chain with 2 - 14 C-atoms in which one or more C-atoms can be replaced by cyclohexyl rings, phenyl or heterocycles, as well as of their in vivo-hydrolysable carboxylic acid derivatives for the preparation of medicaments with fibrinogen-lowering action.

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