Use of amide derivative of ge 2270 factor a3 for the...

Details Use of amide derivative of ge 2270 factor a3 for the... Use of amide derivative of ge 2270 factor a3 for the...

A - Human Necessities

61

K

A61K 38/12 (2006.01) A61P 17/10 (2006.01)

Patent

CA 2489705

Use of the compound of formula (I) and the pharmaceutically acceptable addition salts thereof for the manufacture of a medicament for topical treatment or 5 prevention of acne formula (I) wherein: R represents methoxymethyl, R1 represents methyl, Rz represents methyl, Y represents the group formula (II) The compound of formula (I) and the pharmaceutically acid addition salts thereof show selective activity against propionibacterium acne and are suitable for use in a method of treament or prevention of acne.

L'invention porte sur l'utilisation d'un composé de formule (I) et de ses sels acidifiants, pharmacocompatibles pour la fabrication d'un médicament à usage topique de traitement ou de prévention de l'acné. Dans ladite formule: R représente méthoxyméthyle, R1 représente méthyle, Rz représente méthyle, Y représente le groupe de formule (II). Le composé de formule (I) et ses sels acidifiants présentent une activité sélective contre l'acné à propionibacterium et conviennent pour le traitement de l'acné.

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