Use of amino acids for the treatment and prophylaxis of...

A - Human Necessities – 61 – K

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A61K 31/195 (2006.01)

Patent

CA 2181923

The present invention provides a method and composition for treating or preventing pathogenic effects in a mammal caused by intracellular calcium overload comprising administering to a mammal at least one amino carboxylic acid or its physiologically acceptable salt in an amount effective to treat calcium overload. By effectively treating intracellular calcium overload, the present invention can advantageously prevent cell lysis and irreversible cell damage, especially in mammals suffering from a disease condition associated with or resulting from insufficient oxygenation.

Procédé et préparation permettant de traiter ou de prévenir chez les mammifères les effets pathogènes de l'accumulation calcique intracellulaire, consistant à administrer à un mammifère au moins un acide aminocarboxylique ou son sel physiologiquement acceptable, en une quantité permettant de traiter l'accumulation calcique intracellulaire. Par le traitement efficace de ce dysfonctionnement, la présente invention permet de prévenir la lyse cellulaire et les endommagements irréversibles des cellules, notamment chez des mammifères présentant des états pathologiques associés à une oxygénation insuffisante ou en résultant.

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