Use of aminoalcohol derivatives in the treatment of liver...

A - Human Necessities – 61 – K

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Details

A61K 31/661 (2006.01) A61K 31/13 (2006.01) A61K 31/133 (2006.01) A61P 1/16 (2006.01) A61P 31/12 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2221075

The present invention discloses a method for the treatment of liver diseases, comprising administering an effective amount of an aminoalcohol of the following formula (1) or a salt thereof: Image wherein R1 represents a hydrogen atom or a phosphono group, R2 represents a hydrogen atom or a group -(CH2)n-OR1, and n represents an integer between 2 and 5 inclusive. The present invention also relates to the use of the compound in the manufacture of a remedy for the treatment of liver diseases. This compound exhibits hepatocyte proliferation activity and liver disorder restoring effect, and thus is useful for the treatment of acute hepatitis, chronic hepatitis, hepatic cirrhosis, etc.

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