Use of amylin in pharmaceutical screens

Details Use of amylin in pharmaceutical screens Use of amylin in pharmaceutical screens

C - Chemistry, Metallurgy

12

Q

C12Q 1/18 (2006.01) C07K 14/47 (2006.01) C07K 14/575 (2006.01) C07K 14/74 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2130125

Abstract This invention describes a series of assays useful in evaluating the efficacy of agents which inhibit the neurotoxic effects of .beta.-amyloid peptide. These assays employ amyloidogenic amylin or .beta.2-microglobulin as the target protein instead of the .beta.-amyloid peptide.

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