A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/585 (2006.01) A61K 31/58 (2006.01) A61P 9/00 (2006.01) A61P 9/12 (2006.01)
Patent
CA 2407699
The present invention provides methods for the treatment or prophylaxis of one or more aldosterone-mediated pathogenic effects in a subject suffering from or susceptible to the pathogenic effect or effects wherein the subject has one or more conditions selected from the group consisting of a sub-normal endogenous aldosterone level, salt sensitivity and an elevated dietary sodium intake. The methods comprise administering to the subjects a therapeutically-effective amount of one or more aldosterone antagonists.
La présente invention concerne des méthodes de traitement curatif ou préventif d'un ou de plusieurs effets pathogènes induits par l'aldostérone chez un sujet souffrant de ces effets ou exposé à ces effets. Ledit sujet présente une ou plusieurs des manifestations suivantes: niveau d'aldostérone endogène inférieur à la normale, sensibilité au sel et absorption accrue de sodium alimentaire. Les méthodes selon l'invention consiste à administrer au sujet une dose efficace au plan thérapeutique d'un ou plusieurs antagonistes de l'aldostérone.
Fedde Kenton N.
Funder John W.
Garthwaite Susan M.
Rocha Ricardo
Roniker Barbara
Pharmacia Corporation
Smart & Biggar
LandOfFree
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