A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/395 (2006.01) A01K 67/02 (2006.01) A61K 31/365 (2006.01) A61K 31/7076 (2006.01) A61K 31/7088 (2006.01) A61P 9/00 (2006.01) A61P 9/04 (2006.01) C12Q 1/00 (2006.01) C12Q 1/02 (2006.01) G01N 33/50 (2006.01) G01N 33/68 (2006.01)
Patent
CA 2599783
The present invention relates to the use of at least one Epac (Exchange Protein directly Activated by cAMP) antagonist for the manufacture of a medicament intended for the prevention or the treatment of pathologies selected from the list comprising cardiac hypertrophy, cardiac arrhythmias, valvulopathies, diastolic dysfunction, chronic heart failure, ischemic heart failure, and myocarditis.
La présente invention concerne l~utilisation d~au moins un antagoniste Epac (protéine d~échange directement activée par cAMP) pour la fabrication d~un médicament destiné à la prévention et au traitement de pathologies sélectionnées à partir d'une liste comprenant l'hypertrophie cardiaque, les arythmies cardiaques, les valvulopathies, le dysfonctionnement diastolique, l~insuffisance cardiaque chronique, l~insuffisance cardiaque ischémique et la myocardite.
Gastineau Monique
Lezoualc'h Frank
Morel Eric
Vandecasteele Gregoire
Goudreau Gage Dubuc
Inserm (institut National de La Sante Et de La Recherche Medical
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