A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/395 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2683452
The present invention relates to the use of at least one antibody, or a functional fragment thereof, capable of binding to the CXCR4 protein and thus of inhibiting tumour growth, for the preparation of a medicament for use in the treatment of cancer. The invention also relates to a composition for treating cancer, comprising, as active ingredient, at least one anti-CXCR4 antibody, or a functional fragment thereof, capable of binding to the CXCR4 protein and/or of inhibiting the angiogenic and/or proliferative activity thereof. More particularly, said antibodies consist of the MAB 173 antibody.
La présente invention a pour objet l'utilisation d'au moins un anticorps, ou l'un de ses fragments fonctionnels, capable de se lier à la protéine CXCR4 et ainsi d'inhiber la croissance tumorale pour la préparation d'un médicament destiné au traitement du cancer. L'invention vise également un composition pour le traitement du cancer, comprenant à titre de principe actif au moins un anticorps anti-CXCR4, ou l'un de ses fragments fonctionnels, capable de se lier à la protéine CXCR4 et/ou d'inhiber son activité angiogénique et/ou proliférative. Plus particulièrement, lesdits anticorps consistent en l'anticorps MAB 173.
Goudreau Gage Dubuc
Pierre Fabre Medicament
LandOfFree
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