A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/70 (2006.01) A61P 3/10 (2006.01)
Patent
CA 2552954
The present invention relates to a method of preventing and/or treating diabetes type 2, also, it relates to a method of augmenting Glut4 phosphorylation and Glut4 translocation to a target cell membrane to enhance insulin signal in a signal transduction pathway; further, it relates to a simplified and inexpensive process of obtaining extract and thereafter selectively, its active n-butanol fraction and active molecule Lupinoside PA (LPA4), useful in preventing and/or treating diabetes type 2; and lastly, a pharmaceutical composition thereof.
La présente invention concerne un procédé pour prévenir et/ou traiter un diabète de type 2, un procédé pour augmenter la phosphorylation et la translocation de Glut4 sur une membrane cellulaire cible, afin d'augmenter le signal de l'insuline dans une voie de transduction du signal, ainsi qu'un procédé simplifié et économique pour obtenir un extrait, puis ensuite de manière sélective sa fraction n-butanol active et molécule active Lupinoside PA (LPA4), utilisés pour prévenir et/ou traiter un diabète de type 2, et enfin une composition pharmaceutique de ceux-ci.
Bandopadhyay Santu
Bandyopadhyay Arun
Bhanu Giri Bir
Bhattacharya Samir
Biswas Tanushree
Council Of Scientific And Industrial Research
Ridout & Maybee Llp
LandOfFree
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