Use of an immunoglobulin-producing cell line to gererate...

Details Use of an immunoglobulin-producing cell line to gererate... Use of an immunoglobulin-producing cell line to gererate...

C - Chemistry, Metallurgy

12

N

C12N 15/00 (2006.01) C12N 5/078 (2010.01) C12N 15/01 (2006.01) C12Q 1/68 (2006.01) C40B 40/02 (2006.01) C12N 5/10 (2006.01) C12N 15/13 (2006.01) C12N 15/63 (2006.01) C40B 30/00 (2006.01)

Patent

CA 2675802

The invention relates to a method for preparing an antibody-producing cell line capable of directed constitutive hypermutation of a specific nucleic acid region, comprising the steps of: a) screening a clonal cell population for V gene diversity; b) isolating one or more cells which display V gene diversity and comparing the rate of accumulation of mutations in the V genes and other genes of the selected cells; and c) selecting a cell in which the rate of V gene mutation exceeds that of other gene mutation.

Affiliated with

Also associated with

Rating

Use of an immunoglobulin-producing cell line to gererate... does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Use of an immunoglobulin-producing cell line to gererate..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Use of an immunoglobulin-producing cell line to gererate... will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-2063626