A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/08 (2006.01) A61F 2/06 (2006.01) A61P 9/14 (2006.01) A61P 17/02 (2006.01)
Patent
CA 2582048
The invention provides a method for preventing and/or reducing the formation of neointima comprising delivering to cells of an individual angiotensin-(1-7) or a functional part, derivative and/or analogue thereof, whereby use is made a delivery vehicle which comprises a means for releasing angiotensin-(1-7) or a functional part, derivative and/or analogue thereof. The invention also relates to a delivery vehicle for preventing and/or reducing the formation of neointima, wherein the delivery vehicle comprises an implantable device which device comprises a means for releasing angiotensin-(1-7) or a functional part, derivative and/or analogue thereof.
La présente invention décrit une méthode de prévention et/ou de ralentissement de la formation d~une néointima, qui comprend le relargage dans les cellules d'une angiotensine-(1-7) ou d'une partie fonctionnelle, d'un dérivé et/ou d'un analogue de cette dernière. Un dispositif adapté au dit relargage est employé. La présente invention décrit également un dispositif de relargage destiné à la prévention et/ou au ralentissement de la formation d~une néointima. Ledit dispositif comprend une partie implantable permettant de relarguer l~angiotensine-(1-7) ou une partie fonctionnelle, un dérivé et/ou un analogue de cette dernière.
Henning Robert Henk
Pinto Yigal-Martin
Roks Antonius Jacobus Marinus
Van Gilst Wiekert Hendrikus
Borden Ladner Gervais Llp
Stichting Klinische Farmacologie Groningen
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