A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/41 (2006.01) A61K 31/415 (2006.01) A61K 31/4174 (2006.01) A61K 31/4178 (2006.01) A61K 31/4184 (2006.01) A61K 31/44 (2006.01) A61K 31/4439 (2006.01) A61K 31/47 (2006.01) A61K 31/4709 (2006.01) A61K 31/505 (2006.01) A61K 31/506 (2006.01) A61K 31/519 (2006.01) A61K 38/04 (2006.01)
Patent
CA 2277018
Angiotensin II receptor antagonists are useful in reducing and preventing mortality and sudden cardiac death in symptomatic heart failure patients. Losartan potassium has been shown to reduce mortality and sudden cardiac death in this patient population. Additionally, losartan potassium has been shown to reduce the need for hospitalization of symptomatic heart failure patients.
La présente invention concerne des antagonistes de récepteurs d'angiotensine II utilisés dans la réduction et la prévention de la mortalité et la mort cardiaque soudaine chez des patients présentant des insuffisances cardiaques symptomatiques. Le losartan potassique s'est avéré réduire la mortalité et la mort cardiaque soudaine dans cette population de patients. En outre, le losartan potassique s'est avéré réduire le besoin d'hospitalisation pour les patients présentant des insuffisances cardiaques symptomatiques.
Beere Polly A.
Chang Paul I.
Pitt Bertram
Rucinska Ewa J.
Segal Robert
Merck & Co. Inc.
Merck Sharp & Dohme Corp.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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