Use of anti-cd100 antibodies

Details Use of anti-cd100 antibodies Use of anti-cd100 antibodies

A - Human Necessities

61

K

A61K 39/395 (2006.01) A61P 37/06 (2006.01) C07K 16/28 (2006.01) G01N 33/577 (2006.01)

Patent

CA 2514226

The invention relates to the use a BD16 and/or BB18 anti-CD100 antibody or of a chimeric or humanized or human form thereof, or a fragment thereof, for the therapy or diagnosis of a central nervous system disorder, more particularly a myelin disorder or a disease that affects oligodendrocytes, such as multiple sclerosis or HTLV-1 associated myelopathy or peripheral myelinating cells.

L'invention concerne l'utilisation d'un anticorps anti-CD 100 BD16 et/ou BB18 ou d'une forme chimère, humanisée ou humaine de celui-ci, ou d'un fragment de celui-ci, pour le traitement ou le diagnostic d'un trouble du système nerveux central, plus particulièrement d'un trouble ou d'une maladie d'ordre myélinique qui affecte les oligodendrocytes, de type sclérose en plaques ou myélopathie associée au HTLV-1, ou qui affecte les cellules de myélinisation périphériques.

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