Use of anti-tnf.alpha.antibodies and another drug

Details Use of anti-tnf.alpha.antibodies and another drug Use of anti-tnf.alpha.antibodies and another drug

A - Human Necessities

61

K

A61K 45/08 (2006.01) A61K 39/395 (2006.01) A61P 29/00 (2006.01) C07K 16/24 (2006.01)

Patent

CA 2385777

The present invention is directed to a method of treating disorders in which TFN.alpha. activity is detrimental via biweekly, subcutaneous administration of human antibodies, preferably recombinant human antibodies, that specifically bind to human tumor necrosis factor a (hTNF.alpha.) in combination with another drug which is useful for treating the disorder. An antibody of the invention can be a full-length antibody or an antigen- binding portion thereof. Kits containing a pharmaceutical composition and instructions for dosing are also encompassed by the invention.

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