Use of anti-vegf agents in the treatment of endometriosis

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/00 (2006.01) A61K 31/138 (2006.01) A61K 31/56 (2006.01) A61K 31/57 (2006.01) A61K 31/70 (2006.01) A61K 38/17 (2006.01) A61K 38/19 (2006.01) A61K 39/395 (2006.01) C07K 16/24 (2006.01)

Patent

CA 2191070

Disclosed are: a composition for use in the treatment of endometriosis, comprising an agent capable of interfering with the production and/or activity of VEGF, and a physiologically acceptable carrier substance; a composition for the treatment of endometriosis comprising an agent which inhibits the activation and/or recruitment of peritoneal macrophages, and a physiologically acceptable carrier, and methods of making the compositions and their use in the treatment of endometriosis.

On décrit une composition utile dans le traitement de l'endométriose, comprenant un agent susceptible de contrecarrer la production et/ou l'activité du facteur de croissance des cellules endothéliales, ainsi qu'un excipient acceptable sur le plan physiologique; on décrit également une composition destinée au traitement de l'endométriose comprenant un agent inhibant l'activation et/ou la mobilisation des macrophages péritonéaux, ainsi qu'un excipient acceptable sur le plan physiologique; on décrit encore des procédés de fabrication de ces compositions ainsi que l'utilisation de celles-ci dans le traitement de l'endométriose.

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