A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 39/395 (2006.01) A61P 19/10 (2006.01) C07K 16/22 (2006.01) C07K 16/28 (2006.01)
Patent
CA 2491053
This invention relates to antagonists of the placental growth factor receptor and signalling thereof, pharmaceutical compositions containing such antagonists and the use of such antagonists to prevent bone loss or bone mass and to enhance bone healing including the treatment of conditions which present with low bone mass and/or bone defects in vertebrates, and particularly mammals, including humans.
L'invention concerne des antagonistes du récepteur de croissance placentaire et leur signalisation, des compositions pharmaceutiques contenant de tels antagonistes et l'utilisation de tels antagonistes pour prévenir la déperdition osseuse ou la masse osseuse et pour favoriser la guérison osseuse, y compris le traitement d'états accompagnant une masse osseuse réduite et/ou des défectuosités osseuses chez des vertébrés et notamment des mammifères, y compris chez l'homme.
Bouillon Roger
Carmeliet Gertrudis
Carmeliet Peter
Collen Desire
Fetherstonhaugh & Co.
K.u.leuven Research & Development
Vlaams Interuniversitair Instituut Voor Biotechnologie Vzw
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