Use of antibodies to the gamma 2 chain of lallminin 5 to...

Details Use of antibodies to the gamma 2 chain of lallminin 5 to... Use of antibodies to the gamma 2 chain of lallminin 5 to...

A - Human Necessities

61

K

A61K 39/395 (2006.01) C07K 16/18 (2006.01) G01N 33/574 (2006.01) G01N 33/68 (2006.01)

Patent

CA 2502088

The present invention provides a methods and compositions for inhibiting tumor growth and/or metastasis involving the administering to a subject with a laminin 5-secreting tumor of an amount effective to inhibit tumor growth and/or metastasis of an antibody that binds to one or more epitopes of the laminin 5 .gamma.2 chain.

L'invention concerne des méthodes et des compositions permettant d'inhiber une croissance tumorale et/ou des métastases. Ces méthodes impliquent l'administration, à un sujet souffrant d'une tumeur qui sécrète la laminine 5, d'une quantité efficace d'un anticorps afin d'inhiber une croissance tumorale et/ou des métastases, ledit anticorps se liant à un ou plusieurs épitope(s) de la chaîne ?2 de la laminine 5.

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