Use of antisense oligonucleotides to inhibit the expression...

C - Chemistry – Metallurgy – 07 – H

Patent

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C07H 21/04 (2006.01) A61K 48/00 (2006.01) C12N 15/00 (2006.01) C12N 15/11 (2006.01)

Patent

CA 2495298

New antisense oligonucleotide compounds inhibit expression of Akt-1 and also induce cytotoxicity in several cancer cell lines.

L'invention concerne de nouveaux composés oligonucléotidiques antisens pouvant inhiber l'expression de Akt-1 et également induire une cytotoxicité dans plusieurs lignées cellulaires cancéreuses.

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