Use of antiseptic active principles in polymethyl...

A - Human Necessities – 61 – L

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A61L 24/06 (2006.01)

Patent

CA 2531488

Th invention concerns the use of polyhexamethylene biguanide in PMMA bone cements, which preferably do not contain antibiotics. Said cements exhibit a concentration of active principle not exceeding 1 wt. % relative to the total weight of the cement, that is a concentration sufficiently high to prevent microbial colonization of the cement surface. Said cements do not cause durable alteration of the healing process.

L'invention concerne l'utilisation de polyhexaméthylène biguanide dans des ciments osseux en PMMA, qui, de préférence, ne contiennent pas d'antibiotiques. Ces ciments présentent une concentration de principe actif ne dépassant pas 1 % en poids par rapport au poids total du ciment, c'est-à-dire une concentration suffisamment élevée pour empêcher une colonisation microbienne de la surface du ciment. Ces ciments n'affectent pas le processus de cicatrisation de manière durable.

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