A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 38/17 (2006.01) A61P 1/04 (2006.01) A61P 3/10 (2006.01)
Patent
CA 2748493
The present invention is related with the field of the medicine, particularly with the use of an APL peptide or its analogues derived from the human heat shock protein of 60 kDa, for the manufacture of a pharmaceutical composition for the treatment of Crohn's disease, ulcerative colitis and diabetes mellitus type 1. This peptide is biodistributed into the gastrointestinal tract and also promotes the induction of apoptosis in activated intestinal lamina propria and peripheral blood T cells of patients with Crohn's disease. Furthermore, this peptide induces apoptosis in mononuclear cells of patients with diabetes mellitus type 1.
La présente invention concerne le domaine de la médecine, en particulier avec l'utilisation d'un peptide de type APL dérivé de la protéine de choc thermique de 60 kDa humaine, ou de ses analogues pour la fabrication d'une composition pharmaceutique destinée au traitement de la maladie de Crohn, la colite ulcéreuse et le diabète sucré de type I. Ledit peptide se réparti biologiquement dans le tractus gastro-intestinal et favorise l'induction de l'apoptose de lymphocytes T activés de la couche intestinale propre et du sang périphérique de patients atteints de la maladie de Crohn. De plus, ce peptide induit l'apoptose dans des cellules mononucléaires de patients atteints de diabète sucré de type I.
Barbera Betancourt Ariana
Dominguez Horta Maria Del Carmen
Falcon Cama Viviana
Lorenzo Perez Norailys
Menendez Valdes Ivon
Centro de Ingenieria Genetica Y. Biotecnologia
Deeth Williams Wall Llp
LandOfFree
Use of apl-type peptide for treating intestinal inflammatory... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Use of apl-type peptide for treating intestinal inflammatory..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Use of apl-type peptide for treating intestinal inflammatory... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1836108