Use of app modulators for the manufacture of a medicament...

Details Use of app modulators for the manufacture of a medicament... Use of app modulators for the manufacture of a medicament...

A - Human Necessities

61

K

A61K 31/47 (2006.01) A61K 31/335 (2006.01) A61K 31/365 (2006.01) A61K 31/71 (1990.01)

Patent

CA 2126083

Agents which modulate or affect the intracellular trafficking and processing of proteins in the mammalian cell can be utilized to affect the trafficking and processing of APP, thereby inhibiting production of Alzheimer type amyloidosis. Particularly useful agents are chloroquine and its related derivatives such as primaquine.

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