A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 47/48 (2006.01) A61K 31/196 (2006.01) A61K 31/475 (2006.01) A61K 31/704 (2006.01) A61K 47/42 (2006.01) A61P 35/00 (2006.01)
Patent
CA 2614687
Conjugates comprising carriers selected from the group consisting of aprotinin, a biologically active aprotinin fragment, Angiopep-1, Angiopep-2 and biologically active analogs, derivatives or fragments thereof and a label or drug are disclosed Said conjugates increase the potency of the drug and modify the pharmacokinetics of the drug or label. The use of these conjugates in the treatment and diagnosis of cancer is described
L'invention porte sur des conjugués comprenant des véhicules choisis dans le groupe composé de l'aprotinine, d'un fragment biologiquement actif de l'aprotinine, de l'Angiopep-1, de l'Angiopep-2 et d'analogues biologiquement actifs, de dérivés ou de fragments de cette dernière, et sur une étiquette ou un médicament. Lesdits conjugués augmentent la puissance du médicament et modifient la pharmacocinétique du médicament ou de l'étiquette. L'invention concerne également l'utilisation desdits conjugués dans le traitement et le diagnostic du cancer.
Beliveau Richard
Che Christian
Demeule Michel
Regina Anthony
Angiochem Inc.
Fasken Martineau Dumoulin Llp
LandOfFree
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