Use of arginase inhibitors in the treatment of asthma and...

Details Use of arginase inhibitors in the treatment of asthma and... Use of arginase inhibitors in the treatment of asthma and...

A - Human Necessities

61

K

A61K 31/69 (2006.01) A61K 31/198 (2006.01) A61P 11/06 (2006.01) A61P 37/08 (2006.01)

Patent

CA 2669300

The present invention relates to the use of an arginase inhibitor for the preparation of a medicament for the prophylactic maintenance therapy of an asthmatic or allergic patient by preventing obstruction of upper and lower airways, in particular allergen-induced bronchial obstruction and/or airway hyperresponsiveness. The patients are either asthmatic or have allergic rhinitis. Preferably, the arginase inhibitor is 2 (S) -amino-6-boronohexanoic acid (ABH).

La présente invention porte sur l'utilisation d'un inhibiteur de l'arginase pour la préparation d'un médicament pour la thérapie d'entretien prophylactique d'un patient asthmatique ou allergique par la prévention de l'obstruction des voies respiratoires supérieures et inférieures, en particulier l'obstruction des bronches induite par un allergène et/ou une hypersensibilité des voies respiratoires. Les patients soit sont asthmatiques, soit ont une rhinite allergique. De préférence, l'inhibiteur de l'arginase est l'acide 2(S)-amino-6-boronohexanoïque (ABH).

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