A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/397 (2006.01) A61P 25/28 (2006.01)
Patent
CA 2447884
Methods of preventing, treating, or ameliorating symptoms of Alzheimer's Disease, regulating production or levels of amyloid .beta. (A.beta.) peptides and/or regulating the amount of ApoE isoform 4 in the bloodstream and/or brain are provided which include the step of administering to a subject in need of such treatment an effective amount of a composition including at least one compound represented by Formulae (I-X) disclosed herein.
L'invention concerne des procédés permettant de prévenir, de traiter ou d'améliorer des symptômes de la maladie d'Alzheimer, de réguler la production ou les niveaux de peptides .beta. amyloïde (A.beta.) et/ou de réguler la quantité d'isoforme 4 de l'ApoE dans le circuit sanguin et/ou le cerveau. Ces procédés comprennent l'étape consistant à administrer à un sujet qui a besoin d'un tel traitement une quantité efficace d'une composition comprenant au moins un composé représenté par les formules (I-X).
Davis Harry R.
Merkel Laura B.
Parker Eric Mcfee
Van Heek Margaret
Wong Gwendolyn Tse
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
Schering Corporation
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