Use of b cell expansion agents in generating antibodies

Details Use of b cell expansion agents in generating antibodies Use of b cell expansion agents in generating antibodies

C - Chemistry, Metallurgy

12

P

C12P 21/04 (2006.01)

Patent

CA 2627305

A method for efficiently generating antibodies immunizes an animal with a target antigen and a B cell expansion agent, such as an anti-CD40 agonist. The antibodies generated from this method are useful as therapeutic agents, diagnostic agents or research reagents in a variety of diseases and conditions.

L'invention concerne une méthode permettant de générer efficacement des anticorps qui immunisent un animal au moyen d'un antigène cible et d'un agent d'expansion de cellules B, tel qu'un agoniste anti-CD40. Les anticorps générés à partir de cette méthode sont utilisés comme agents thérapeutiques, agents diagnostiques ou réactifs de recherche dans une variété de maladies et d'états pathologiques.

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