Use of benzothiophenes for lowering serum cholesterol

Details Use of benzothiophenes for lowering serum cholesterol Use of benzothiophenes for lowering serum cholesterol

A - Human Necessities

61

K

A61K 31/445 (2006.01) A61K 31/38 (2006.01) A61K 31/40 (2006.01) A61K 31/4025 (2006.01) A61K 31/4535 (2006.01) A61K 31/55 (2006.01)

Patent

CA 2112017

Use of a compound of formula (I): (See formula I) wherein n is 0, 1 or 2; R is hydroxyl, methoxy, C1-C7 alkanoyloxy, C3-C7 cycloalkanoyloxy, (C1-C6 alkoxy)-C1-C7 alkanoyloxy, substituted or unsubstituted aroyloxy, or substituted or unsubstituted aryloxycarbonyloxy; R1 is hydrogen, hydroxyl, chloro, bromo, methoxy, C1- C7 alkanoyloxy, C3-C7 cycloalkanoyloxy, (C1-C6 alkoxy)-C1-C7 alkanoyloxy, substituted or unsubstituted or aroyloxy, or substituted or unsubstituted aryloxycarbonyloxy; R2 is a heterocyclic ring selected from the group consisting of pyrrolidino, piperidino, or hexamethyleneimino; or a pharmaceutically acceptable salt or solvate thereof; in the preparation of a medicament useful for lowering serum cholesterol levels in animals.

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