Use of benzotriazines as pla2 inhibitors, new...

C - Chemistry – Metallurgy – 07 – D

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C07D 253/10 (2006.01) A61K 31/53 (2006.01)

Patent

CA 2152614

Summary: Use of compounds of the- formula I Image (I), in which R1 signifies an amino, C1-C6-alkylamino, di- C1-C6-alkylamino or a hydroxyl group, R2 and R3, which are the same or different, each hydrogen, halogen, C1-C6-alkyl, C1-C6-alkoxy, cyano, carboxyl, halogen- C1-C6-alkyl, cyano-C1-C6-alkyl, carboxy-C1-C6-alkyl, C1-C6-alkyl, hydroxyl, carboxy-C1-C6-alkoxy, C1-C6- alkoxycarbonyl-C1-C6-alkoxy or aminocarbonyl-C1-C6- alkoxy, C1-C6-alkylaminocarbonyl-C1-C6-alkoxy or di- C1-C6-alkylaminocarbonyl-C1-C6-alkoxy and n the number 0 or 1, their tautomers, as well as salts with non- toxic acids or bases, for the preparation of medi- caments with PLA2-inhibiting action, new compounds and process for their preparation.

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