Use of bipolar trans carotenoids as a pretreatment and in...

A - Human Necessities – 61 – K

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A61K 31/194 (2006.01) A61P 9/10 (2006.01)

Patent

CA 2683760

The subject application relates to methods of treatment of peripheral vascular disease (PVD) as well as ischemic osteonecrosis, peritoneal ischemia, chronic ocular disease, macular degeneration, or diabetic retinopathy, comprising administering a therapeutically effective amount of a trans carotenoid. The invention also relates to the use of such carotenoids as pretreatments for mammals at risk of an ischemic event.

L'invention concerne des procédés de traitement de pathologies vasculaires périphériques (PVP) ainsi que l'ostéonécrose ischémique, l'ischémie péritonéale, les pathologies oculaires chroniques, la dégénérescence maculaire ou la rétinopathie diabétique, comprenant l'administration d'une quantité thérapeutiquement efficace d'un transcaroténoïde. L'invention concerne également l'utilisation de ces caroténoïdes en tant que traitements préalables pour des mammifères exposés à un risque d'évènement ischémique.

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