Use of bradycardiac agents in the treatment of myocardial...

A - Human Necessities – 61 – K

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A61K 31/55 (2006.01) A61P 9/00 (2006.01)

Patent

CA 2404120

The present invention relates to the new use of bradycardiac substances such as a Ca++ channel blocker, beta-receptor blocker or i f channel blocker, the i f channel blockers being preferred, optionally in combination with a cardioactive substance for inducing the regression of myocardial diseases accompanied by hypertrophy, particularly for the treatment of idiopathic hypertrophic cardiomyopathies (HCM) in humans and domestic pets.

La présente invention concerne une utilisation nouvelle de substances bradycardiques telles qu'un bloquant de canal Ca<++>, des bloquants de béta-récepteurs, ou des bloquants de canal if, les bloquants de canal if étant les bloquants préférés. Lesdites substances bradycardiques peuvent être utilisées en combinaison avec une substance agissant sur le coeur de manière à provoquer une régression de maladies cardiaques accompagnées d'hypertrophie, en particulier pour le traitement de cardiomyopathies idiopathiques hypertrophiques (HCM) chez l'homme et les animaux domestiques.

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