Use of bromelain proteases for inhibiting blood coagulation

Details Use of bromelain proteases for inhibiting blood coagulation Use of bromelain proteases for inhibiting blood coagulation

A - Human Necessities

61

K

A61K 38/48 (2006.01) A61P 7/02 (2006.01)

Patent

CA 2333252

The invention relates to the use of bromelain proteases for inhibiting the blood coagulation system, notably for stimulating plasmin production, inhibiting fibrin production and inhibiting the adhesion of human thrombocytes to endothelial cells. The basic proteases, which can be isolated from pure bromelain, have proved to be especially suitable proteases.

L'invention concerne l'utilisation de bromélaïne protéases pour inhiber le système de coagulation du sang, notamment pour stimuler la formation de plasma, pour inhiber la formation de fibrine et l'adhésion de thrombocytes humains sur des cellules endothéliales. Les protéases basiques, pouvant être isolées à partir de la bromélaïne pure, se sont avérées des protéases particulièrement appropriées.

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