A - Human Necessities – 61 – P
Patent
A - Human Necessities
61
P
A61P 33/06 (2006.01) A61K 31/45 (2006.01)
Patent
CA 2564570
The present invention relates to a method for treating plasmodium related diseases comprising administering a compound capable of inhibiting tyrosine kinases, to a human in need of such treatment. Such compounds can be chosen from tyrosine kinase inhibitors including c-kit inhibitors and more particularly non-toxic, selective and potent tyrosine kinases inhibitors. Preferably, said inhibitor is unable to promote death of IL-3 dependent cells cultured in presence of IL-3.
La présente invention porte sur une méthode de prévention ou de traitement de maladies imputables au plasmodium, cette méthode consistant à administrer un composé capable d'inhiber des tyrosine kinases. Ces composés peuvent être choisis à partir des inhibiteurs de la tyrosine kinase comprenant des inhibiteurs de c-kit et, plus particulièrement, à partir d'inhibiteurs des tyrosine kinases non toxiques, sélectifs et puissants. De préférence, cet inhibiteur est capable de favoriser la mort des cellules dépendant d'IL-3 et mises en culture en présence d'IL-3.
Kinet Jean-Pierre
Moussy Alain
Ab Science
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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