Use of calcitonin as combined treatment therapy for the...

Details Use of calcitonin as combined treatment therapy for the... Use of calcitonin as combined treatment therapy for the...

A - Human Necessities

61

K

A61K 38/23 (2006.01) A61K 31/519 (2006.01) A61K 31/573 (2006.01) A61K 31/58 (2006.01) A61K 39/395 (2006.01) A61P 29/00 (2006.01)

Patent

CA 2603156

The use is provided of a calcitonin in the preparation of a medicament for the treatment of an inflammatory disease or condition. The calcitonin may be selected from the group consisting of human, salmon, eel, porcine, bovine, or chicken calcitonin or a derivative, a fragment or a variant thereof. The inflammatory disease or condition may be rheumatoid arthritis (RA), juvenile rheumatoid arthritis (JRA), osteoarthritis, psoriasis, psoriatic arthritis, ankylosing spondylitis (AS), lupus erythamatosis, multiple sclerosis (MS), asthma, or immuno-suppressive therapy (e.g. post transplantation surgery). The treatment may also comprise administration of a glucocorticoid, an anti- rheumatic drug or an antibody.

L'invention se rapporte à l'utilisation d'une calcitonine dans la préparation d'un médicament destiné au traitement d'une pathologie ou d'un état inflammatoire. La calcitonine peut être sélectionnée dans le groupe constitué de calcitonine humaine, de saumon, d'anguille, porcine, bovine ou de poulet ou d'un de ses dérivés, de ses fragments ou d'une de ses variantes. La maladie ou l'état inflammatoire peuvent être de la polyarthrite rhumatoïde (PR), de la polyarthrite rhumatoïde juvénile (PRJ), de l'ostéoarthrite, du psoriasis, du rhumatisme psoriasique, de la spondylarthrite ankylosante (SA), du lupus érythémateux, la sclérose en plaques, l'asthme, ou une thérapie immunosuppressive (p. ex. une chirurgie post transplantation). Le traitement peut également consister à administrer un glucocorticoïde, un antirhumatismal ou un anticorps.

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