Use of camptothecin derivates for the treatment of...

Details Use of camptothecin derivates for the treatment of... Use of camptothecin derivates for the treatment of...

A - Human Necessities

61

K

A61K 31/4745 (2006.01) A61P 35/00 (2006.01) A61P 35/04 (2006.01)

Patent

CA 2559532

Topoisomerase I inhibitors preferably the camptothecin derivative gimatecan, are administered for the treatment of proliferative diseases according to a once every three day fixed dosing regimens. Furthermore, the invention provides the use of topoisomerase inhibitors to manufacture a medicament for the treatment of a proliferative disease which can be used in a fixed dose treatment regimen.

Selon l'invention, des inhibiteurs de la topoisomérase I sont administrés en vue de traiter des maladies à évolution chronique, selon des schémas posologiques fixes de prise une fois tous les trois jours. L'invention concerne l'utilisation d'inhibiteurs de la topoisomérase pour fabriquer un médicament pouvant être utilisé selon un schéma posologique fixe.

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