Use of carbon nanotube for drug delivery

A - Human Necessities – 61 – K

Patent

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A61K 9/00 (2006.01) A61K 31/00 (2006.01) A61K 47/48 (2006.01)

Patent

CA 2697093

Compositions and methods for administering a therapeutic agent to a mammal are disclosed. The compositions comprise either (i) vesicles comprising an amphiphilic substituted fullerene, wherein the therapeutic agent is present in the vesicle interior or between layers of the vesicle wall, (ii) a substituted fullerene, comprising a fullerene core and a functional moiety, wherein the therapeutic agent is associated with the substituted fullerene, or (iii) carbon nanotubes, wherein the therapeutic agent is associated with the carbon nanotubes.

L'invention porte sur des compositions et des procédés pour administrer un agent thérapeutique à un mammifère. Les compositions comprennent ou bien (i) des vésicules comprenant du fullerène substitué amphiphile, l'agent thérapeutique étant présent dans l'intérieur d'une vésicule ou entre des couches de la paroi de vésicule, ou bien (ii) un fullerène substitué, comprenant un noyau fullerène et une fraction fonctionnelle, l'agent thérapeutique étant associé au fullerène substitué, ou bien (iii) des nanotubes de carbone, l'agent thérapeutique étant associé aux nanotubes de carbone.

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