Use of cationic lipids to generate anti-tumor immunity

Details Use of cationic lipids to generate anti-tumor immunity Use of cationic lipids to generate anti-tumor immunity

A - Human Necessities

61

K

A61K 47/48 (2006.01) A61K 9/127 (2006.01) A61K 39/39 (2006.01) A61K 48/00 (2006.01) A61P 35/00 (2006.01)

Patent

CA 2361459

A method of generating an anti-tumor immune response using a cationic molecule:biologically active molecule complex is provided. In one embodiment, the anti-tumor immune response is a protective, memory-based response. The complex may be administered alone, as the active ingredient in a formulation, or as an adjuvant. The invention also provides for methods of generating an immunostimulatory response against the tumor cell present during treatment by exposing a cationic molecule:biologically active molecule complex to a mammalian cell or a foreign tumor cell.

L'invention concerne un procédé permettant de générer une réponse immunitaire anti-tumorale à l'aide d'un complexe de molécule biologiquement active/ molécule cationique. Selon un mode de réalisation, la réponse immunitaire anti-tumorale est une réponse de protection basée sur la mémoire. Ce complexe peut être administré seul, sous forme d'ingrédient actif dans une formation, ou sous forme d'un adjuvant. L'invention traite aussi de procédés permettant de générer une réponse immunostimulante contre la cellule tumorale présente pendant le traitement en exposant un complexe de molécule cationique/molécule biologiquement active à une cellule de mammifère ou une cellule tumorale étrangère.

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