Use of ccr9, ccl25/teck, and integrin .alpha.-4 in diagnosis...

Details Use of ccr9, ccl25/teck, and integrin .alpha.-4 in diagnosis... Use of ccr9, ccl25/teck, and integrin .alpha.-4 in diagnosis...

C - Chemistry, Metallurgy

12

Q

C12Q 1/68 (2006.01) G01N 33/53 (2006.01) G01N 33/574 (2006.01)

Patent

CA 2694781

The invention relates to methods for determining whether a melanoma will metastasize or has metastasized to the small intestine in a subject by detecting or quantifying the expression of the CCR9, CCL25/TECK, or integrin .alpha.4 gene. Also dis-closed are methods for treating subjects so identified.

L'invention concerne des procédés pour déterminer si un mélanome va avoir des métastases ou a des métastases en rapport à l'intestin grêle chez un sujet en détectant ou quantifiant l'expression du gène CCR9, CCL25/TECK, ou d'intégrine a4. Des procédés pour traiter des sujets ainsi identifiés sont également décrits.

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