Use of cd23 antagonists for the treatment of neoplastic...

A - Human Necessities – 61 – K

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A61K 39/395 (2006.01) A61K 31/00 (2006.01) A61K 31/70 (2006.01) A61K 31/7076 (2006.01) A61K 38/00 (2006.01) A61K 45/00 (2006.01) A61K 45/06 (2006.01) A61P 35/00 (2006.01) A61P 35/02 (2006.01) C07K 16/28 (2006.01)

Patent

CA 2444661

Methods and kits for the treatment of neoplastic disorders comprising the use of a CD23 antagonist are provided. The CD23 antagonist may be used alone or in combination with chemotherapeutic agents. In particularly preferred embodiments the CD23 antagonists may be used to treat B cell chronic lymphocytic leukemia (B-CLL).

L'invention concerne des méthodes et des kits utilisés dans le traitement des troubles néoplasiques, comprenant l'utilisation d'un antagoniste CD23. Cet antagoniste CD23 peut être utilisé seul ou il peut être associé à des agents chimiothérapiques. Dans des modes de réalisation préférés, les antagonistes CD23 peuvent être utilisés pour traiter la leucémie lymphoïde cellules B chronique (LLC-B).

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