Use of cgrp antagonists in treatment and prevention of hot...

A - Human Necessities – 61 – K

Patent

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Details

A61K 31/517 (2006.01) A61K 31/4045 (2006.01) A61K 31/422 (2006.01) A61P 13/00 (2006.01)

Patent

CA 2531407

The invention relates to a method of treatment or prevention of hot flushes in men who underwent castration, e.g. due to androgen ablation treatment in prostate cancer therapy, comprising administration of an effective amount of a CGRP antagonist and/or of a CGRP release inhibitor to the patient, and to the use of said active compounds for the manufacture of a pharmaceutical composition intended to be used in this method.

L'invention concerne un procédé de traitement ou de prévention de bouffées de chaleur chez les hommes ayant subi une stérilisation, par exemple à cause du traitement par ablation des androgènes en thérapie du cancer de la prostate, qui consiste à administrer au patient une dose efficace d'un antagoniste du CGRP et/ou d'un inhibiteur de libération du CGRP ; elle concerne également l'utilisation desdits composés actifs pour fabriquer une composition pharmaceutique destinée à servir dans ce procédé.

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